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Best Stabilized R Lipoic Acid 100mg - Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
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Best Stabilized R Lipoic Acid 100mg -
Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
Stability: The Key to Maximum Benefit the stability of R-Lipoic Acid (RLA) is crucial to its bioavailability.
Routine enivronmental factors, such as temperature, casues less stable forms to "polymerize" and become sticky so that they are less soluable in water, which severely limits the body's absorption of RLA and reduces the nutrient's benefits. Best stabilized R-Lipoic Acid featuring K-RALA, provides greatly enhanced stability which makes this remarkable supplement’s several benefits even more available to your body.
Glucose Metabolism &RLA Glucose has to be metabolized in order to be utilized by the body, and the key spark plug in this process is lipoic acid. RLA helps blood sugar gain entry into muscle cells, and studies have shown that it also helps to normalize blood glucose in insulin resistant subjects. Much of the lipoic acid found in supplements consists of a 50-50 mixture of R- and S-lipoic acid.
Evidence suggests there are advantages to taking pure R-lipoic acid as opposed to the R- and S- mixture. One thing is clear; R-lipoic acid is absorbed better than S-lipoic acid—about 40% to 50% better in one test.
RLA: Universal antioxidant Because R-Lipoic Acid is the only form of lipic acid recognized by the critical mitochondrial enzymes, it’s responsible for most of the lipoic acid’s benefits, including potent anti-aging properties, and protecting brain cells against neurotoxins. A nutrient that helps turn carbohydrates into energy, RLA acts somewhat like a B vitamin in this metabolic role, while it also recycles antioxidant nutrients such as Vitamin C and E.
Unlike better-known antioxidants such as vitamin C and E, RLA is soluble in water AND fat. This unique property allows it to mop up free-radials in the cell, as well as in the membranes surrounding cells (which are especially vulnerable to free-radical attacks).
SUGGESTED USAGE
One (1) to two (2) capsules daily, or as directed by a health care professional.
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Best Stabilized R Lipoic Acid 100mg -
Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
| Supplement Facts | Serving Size: 1 capsule
Servings Per Container: 60 |  | | | %DV | | | D-Biotin | 150 mcg | † | | | R-Lipoic acid (as Potassium R-Lipoate (K-RALA)) | 100 mg | † | | | | †Daily Value not yet established. | |
Other Ingredients: Hydroxypropyl methycelluiose, magnesium silicate hydroxide, magnesium stearate.
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Best Stabilized R Lipoic Acid 100mg -
Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
Editor's rating: 8 out of 10
User's rating:  0%  0%
USER'S OPINION
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Best Stabilized R Lipoic Acid 100mg -
Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
How It Works
How "Sustained Release" works
Using a highly sophisticated process involving mixing and compression, a specialized form of cellulose is combined with ALA, which results in substantial lengthening of the time required by the stomach to digest and release the nutrient into the small intestine. This enables the ALA to be slowly absorbed by the system, thereby maintaining and optimal concentration of effective antioxidant in the bloodstream throughout the day.
FAQ
How “about R-Lipoic” acid?
Alpha Lipoic Acid occurs in two forms, designated "R" and "S". Studies suggest that R-alpha lipoic acid, the natural form, is more biologically active than the S form. Like ALA, RLA recycles antioxidant nutrients, such as vitamin C and E, and helps maintain healthy blood sugar levels when used as part of the diet.- Natural form of alpha lipoic acid - found in humans, animals and plants.
- More rapidly absorbed than S-lipoic acid (the synthetic molecular mirror-image of R-lipoic acid).
- Exhibits potent antioxidant and anti-aging properties.
- Shown to normalize blood glucose in insulin resistant study subjects.
- Protects brain cells against neurotoxins.
Benefits- Supports the body’s defense against rree radicals recycles antioxidant nutrients such as Vitamin C and Vitamin E.
- Helps maintain a healthy blood sugar level when used as part of the diet
Alpha-lipoic Acid––the "Ideal Antioxidant"
The antioxidant potential of a substance is based on a number of criteria, including:
1) Ability to quench specific free-radicals.
2) Ability to bind or "chelate" metal ions that can generate free radicals.
3) Supports function of other antioxidants.
4) Absorption/bioavailability.
5) Concentration in tissues, cells and extra cellular fluids.
6) Ability to function as an antioxidant in fatty and watery environments.
The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.
As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
1) ALA is easily absorbed when consumed orally.
2) ALA is readily converted to DHLA in various tissues.
3) As a pair, ALA and DHLA neutralize superoxide, hydroxyl, peroxyl, and hypochlorus radicals.
4) ALA and DHLA form stable complexes with metal ions such as iron, manganese, copper and zinc ions.
5) ALA and DHLA scavenge free radicals in fatty environments and watery environments.
6) DHLA recycles other important antioxidants.
DHLA-regenerates vitamin C, vitamin E and glutathione
Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.
DHLA is an essential component in the interaction between these antioxidants. Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E. DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form. The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells. DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes. Evidence from animal studies suggests that DHLA protects the brain against free radical damage.
Alpha-lipoic Acid and blood sugar
Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA. In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved. In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.
Safety
Alpha-lipoic acid is considered safe, and no adverse effects have been seen with long-term supplementation.
GUARANTEE/ SHIPPING INFORMATION
Best Stabilized R Lipoic Acid 100mg is shipped in a discrete, unmarked package. Orders are processed immediately and usually take about 3 to 5 working days to be received. We do ask that you try it for 2 to 3 weeks to feel the full effects. Any information received is used only for order processing and shipping purposes. Your information, such as e-mail address, will never be disclosed to a third party.
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Best Stabilized R Lipoic Acid 100mg -
Defends Against Free Radicals, 60 vcaps, (Doctor's Best)
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